G-Protein Targets
April 17-18, 2009
New Orleans, LA

Organized by:  Alan V. Smrcka and Theresa M. Filtz

Sponsored by:  ASPET's Division for Molecular Pharmacology

Early Registration Deadline:  March 17, 2009
 

 

Friday, April 17

 

 8:00 am Introduction & Welcome

Alan V. Smrcka
Theresa M. Filtz

Theme I:  Effector Structure and Mechanism for Regulation  
      Session  Chair:  T. Kendall Harden  
8:10 am           Mechanism of Activation of Phospholipase C Isozymes
 

T. Kendall Harden
Univ of North Carolina

8:50 am           Structure and function of G protein regulated RhoGEFs

John J. G. Tesmer
Univ of Michigan

9:30 am           Molecular Basis for K+ Channel Regulation by Gßγ

Diomedes E. Logothetis
Virginia Commonwealth Univ

10:10 am            Break & Posters
 
 
Theme II:   Novel G Protein Effectors and Regulatory Mechanisms  
      Session Chair:  Paul C. Sternweis  
10:40 am           G12/G13 Activation of Adenylyl Cyclase
 

Lily Jiang
Univ Texas Southwestern Med Ctr

11:20 am           A Novel Signaling Mode for α1A-Adrenergic Receptors
 

Marcos E. Milla
Roche, Palo Alto

12:00 pm Lunch
 
 
 1:30 pm           GIV is a Non-Receptor GEF for Gαi with a Unique Motif that
          Regulates Akt Signaling (Submitted Abstract)
 

Mikel Garcia-Marcos
Univ. California, San Diego

Theme III:  Effector Scaffolding  
      Session Chair:  Terry Hébert  
2:00 pm           Cell Signaling in Space and Time

Graeme Carnegie
Univ. of Washington

2:40 pm           Molecular Chaperones for Kir3 Channel Assembly

Terry Hébert
McGill Univ , Canada

3:20 pm           Break & Posters  
3:40 pm           N-Terminus of Adenylyl cyclase 5 Scaffolds Heterotrimeric
          G-Proteins (Submitted Abstract)
 

Rachna Sadana
Univ of Texas HSC, Houston

  Special Lecture on G Protein BRET Methods:  Application to G Protein Effectors  
4:10 pm     Use of BRET to Monitor G Protein Conformational Changes

Michel Bouvier
Univ of Montreal, Canada

5:10 pm     Posters  

Saturday, April 18

     
Theme IV:  Effector Cell Physiology and Pharmacological Targeting  
      Session Chair:  Alan V. Smrcka  
8:20 am           RhoGEF Regulation in Cells

Philip B. Wedegaertner
Thomas Jefferson Univ

9:00 am           Epac in cAMP-dependent Physiology

Martina Schmidt
Univ Groningen, Netherlands

9:40 am           cAMP Signaling Axes in the Regulation of Pancreatic
          Islet Cell Function (Submitted Abstract)
 

Michelle E. Kimple
Duke Univ Med Ctr

10:10 am           Break & posters
 
 
10:40 am           Pharmacological Targeting of AC

Yoshihiro Ishikawa
UMDNJ-New Jersey Med Sch

11:20 am           Diverse Mechanisms for Inhibition of Gßγ Signaling by
             Proteins, Peptides and Small Molecules

Alan V. Smrcka
Univ of Rochester
 

12:00 pm Lunch
 
 
Theme V:  Physiological Roles of G Protein Effector Systems in vivo  
      Session Chair:  Theresa M. Filtz  
1:30 pm           Role of Adenylyl Cyclase Type 5 in Longevity and Stress
             Resistance

Stephen F. Vatner
UMDNJ-New Jersey Med Sch

2:10 pm           PLC Regulation in the Heart

Elizabeth A. Woodcock
Baker Med Res Inst,  Australia

2:50 pm           Break & posters
 
 
3:20 pm           Chemoattractant Signaling in Myeloid Function

Dianqing (Dan) Wu
Yale Univ

  Plenary Lecture  
4:20 pm     G-Protein Effector Interaction:  A Target for Drug Discovery?

Heidi Hamm
Vanderbilt Univ

 

                            


Deadline Dates

Poster Abstract Submission:  February 10, 2009

Email abstracts to Nwhite@aspet.org with a note indicating that the abstract is for
the G-Protein Targets Colloquium.

Registration:

Before March 17    
  ASPET Member $475.00
  Non-Members $625.00
  Students/Postdoctoral Fellows $100.00
After March 17 & On-site Registration    
  ASPET Member $575.00
  Non-Members $725.00
  Students/Postdoctoral Fellows $200.00

 

ASPET Member Registration - Save time by logging in first!

ASPET Non-Member Registration

     
____________________________________________________________________

Posters for this Colloquium will follow the guidelines set by EB 2009.  The poster-board surface area is 3'8" high and 5'6" wide. Prepare a 6" high headline strip that runs the full width of the poster. Include the title, authors, and affiliations on the strip in letters not less than 1" high. Post a large-typed copy of your abstract in the upper left-hand corner. 

For more information go to the EB  2008 website for presentation information:  http://www.eb2009.org/PosterPresentationGuidelines.htm

 
 

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